EHR4CR: A Semantic Web Based Interoperability Approach for Reusing Electronic Healthcare Records in Protocol Feasibility Studies
نویسندگان
چکیده
A major barrier to repurposing routinely collected data for clinical research is the heterogeneity of healthcare information systems. Electronic Health Record for Clinical Research (EHR4CR) is a European project designed to improve the efficiency of conducting clinical trials. We propose an initial architecture of the EHR4CR Semantic Interoperability Framework using Semantic Web technologies. We used a model-driven engineering approach to build the semantic resources and derived an HL7-based EHR4CR information model. We plan to apply existing ontology modularization techniques for obtaining relevant set of common data elements and clinical terminologies bound to our ERH4CR information model. EHR4CR platform provides semantic interoperability services that facilitate the process of defining eligibility criteria based on standard terminologies and then transforming and executing the user-defined SPARQL queries on RDF triplestore representing local EHRs. We plan to evaluate our semantic interoperability framework for patient eligibility determination in the context of 10 clinical trials running in 11 health institutions.
منابع مشابه
Using electronic health records for clinical research: The case of the EHR4CR project
OBJECTIVES To describe the IMI EHR4CR project which is designing and developing, and aims to demonstrate, a scalable, widely acceptable and efficient approach to interoperability between EHR systems and clinical research systems. METHODS The IMI EHR4CR project is combining and extending several previously isolated state-of-the-art technical components through a new approach to develop a platf...
متن کاملAssessing the Financial Impact of Reusing Electronic Health Records Data for Clinical Research: Results from the EHR4CR European Project
Copyright: © 2016 Dupont D, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Assessing the Financial Impact of Reusing Electronic Health Records Data for Clinical Research: Results from the EHR4CR Europe...
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